Fig. 3

Hepatic ceramide (Cer) and sphingomyelin (SM) levels in mice fed a control or low-methionine choline-deficient (LMCD) diet, and injected either with water (W) or diethylnitrosamine (DEN) (n = 10–11 mice per group). a Cer, b SM, c long-chain (LC) / very long-chain (VLC) Cer ratio. ** P <  0.01, *** P <  0.001