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Table 1 Clinical and biochemical parameters of the study population according to the FG-IR and HOMA-IR indices (positive and negative)

From: Evaluation of lipid ratios and triglyceride-glucose index as risk markers of insulin resistance in Iranian polycystic ovary syndrome women

   FG-IR HOMA-IR
Variables Total PCOS Negative Positive P-value Negative Positive P-value
n = 275 (≥ 8.25) n = 30 (< 8.25) n = 275 (< 2.63) n = 30 (≥ 2.63)
Age (years) 29.94 ± 4.56 29.82 ± 4.55 31.1 ± 4.51 0.14 29.85 ± 4.56 30.77 ± 4.52 0.29
BMI (kg/m2) 26.62 ± 4.19 26.62 ± 4.16 26.63 ± 4.51 0.98 26.66 ± 4.22 26.22 ± 4.01 0.58
Insulin (μU/mL) 4.34 (2.8–7.4) 4 (2.67–6.41) 13.2 (11.9–14.83) < 0.001 4 (2.67–6.41) 13.2 (12.15–14.83) < 0.001
HomoCys (μU/mL) 11.57 (8.87–15.4) 11.9 (9.07–15.4) 9.92 (7.97–14.02) 0.077 11.7 (9.19–15.4) 9.83 (7.68–13.47) 0.04
Free-T (pg/mL) 3.25 ± 1.15 3.25 ± 1.13 3.21 ± 1.38 0.84 3.26 ± 1.15 3.14 ± 1.2 0.59
LH (IU/L) 6.48 (4.25–9.45) 6.48 (4.4–9.5) 6.05 (3.46–8.6) 0.21 6.48 (4.4–9.5) 6.46 (3.44–8.63) 0.34
FSH (IU/L) 6 (4.44–7.55) 6 (4.47–7.54) 6.15 (4–8.79) 0.91 6 (4.47–7.5) 6.6 (4.07–8.83) 0.75
TG (mg/dL) 116 (86–156) 116 (86–156) 117 (81–156.75) 0.71 114 (84–155) 125 (105–205.65) 0.07
FBG (mg/dL) 89.57 ± 9.48 89.58 ± 9.53 89.4 ± 9.15 0.92 88.69 ± 8.87 97.6 ± 11.16 < 0.001
TC (mg/dL) 172.46 ± 36.24 171.56 ± 36.7 180.72 ± 31.1 0.18 171.59 ± 36.26 180.46 ± 35.69 0.20
LDL-C (mg/dL) 98.54 ± 29.08 98.64 ± 29.54 97.63 ± 24.86 0.85 98.12 ± 29.01 102.38 ± 29.86 0.44
HDL-C (mg/dL) 44 (38–49.6) 44 (38–50) 43 (36.25–46.25) 0.18 44 (39–50) 41 (34–47) 0.048
TyG 4.62 (4.62 ± 0.24) 4.62 ± 0.24 4.63 ± 0.23 0.73 4.61 ± 0.23 4.74 ± 0.25 0.005
TG/HDL-C 2.68 (1.84–3.78) 2.68 (1.84–3.72) 2.73 (1.85–4.71) 0.75 2.66 (1.81–3.69) 3.32 (2.18–5) 0.033
TC/HDL-C 4 ± 1.13 3.95 ± 1.12 4.44 ± 1.15 0.024 3.94 ± 1.09 4.55 ± 1.36 0.005
FG-IR 20.76 (11.9–20.76) 21.79 (13.78–34.46) 7.07 (5.57–7.57) < 0.001 21.79 (13.78–34.46) 7.48 (5.57–8.46) < 0.001
HOMA-IR 0.98 (0.61–1.65) 0.89 (0.56–1.43) 3.1 (2.6–3.41) < 0.001 0.89 (0.56–1.42) 3.14 (2.93–3.5) < 0.001
QUICKI 0.39 ± 0.05 0.4 ± 0.04 0.32 ± 0.01 < 0.001 0.4 ± 0.04 0.32 ± 0.01 < 0.001
  1. The cut-off point for QIUCKI index was equal to 0.33 based on 90% percentile (positive < 0.33). Parametric data are shown as mean ± standard deviation. Non-parametric data are given as median and interquartile range [Q1-Q3]